May 2021 » AllergySA

Eosinophils are a type of white blood cell in our body that helps fight off parasitic infections and cancers. They also play a role in allergic reactions. They make up a small fraction of our white blood cells, and the number of eosinophils in our blood can vary over time. If the number of eosinophils in your bloodstream or organs are elevated, you may have an eosinophil-associated disease.

Although many diseases are caused by an increasing number of eosinophils in your body, we will focus on what is, and the background behind eosinophilic asthma.

What is Eosinophilic Asthma (e-asthma)?

Eosinophilic asthma is a subtype of asthma that is normally seen in adults ranging from 35-50 years of age, although it can occur in children and young adults as well. If you have asthma, the number of eosinophils are high in your blood, lung tissue, or mucus and coughed up from your respiratory tract, you likely have e-asthma.

Unfortunately, the cause for e-asthma remains unknown. However, those with e-asthma do not usually have any disease-related allergies that provoke asthma symptoms. There are many ongoing clinical trials that center around therapies to control e-asthma symptoms.

Symptoms

Eosinophilic asthma has similar symptoms to classic asthma. However, the symptoms are more severe and constant. These include:

Shortness of breath
Wheezing
Coughing
Airflow obstruction
Chronic rhinitis with nasal polyps
Inflamed nasal mucous membrane

Diagnosis

If you have severe asthma, levels of eosinophils by analyzing your blood, sputum, saliva, or conducting a bronchial biopsy (tiny forceps passed through a channel of the bronchoscope into your lungs).

Treatments

Although e-asthma has been established for many years, there are now new treatments that can reduce eosinophils.

Biologic therapies that target eosinophils may be prescribed to treat eosinophilic asthma.

Biologics that are currently approved for use in the U.S. include the following

Benralizumab: antibody that binds Interleukin-5 (IL-5) receptors. 12 years and older
Dupilumab: Interleukin-4 (IL-4) and Interleukin-13 (IL-13) inhibitor and binds to the IL-4 alpha receptor. 12 years and older
Mepolizumab: an antibody that recognizes and blocks Interleukin-5 (IL-5). 6 years and older
Reslizumab: an antibody that recognizes and blocks Interleukin-5 (IL-5). 18 years and older

Many treatments and therapies are underway to improve the lives of many with eosinophilic asthma.

If you or someone you know suffer from severe asthma, our board-certified providers are ready to help you find the right treatment for you. Call 210-616-0882 to schedule your appointment today.

Asthma is an extremely common lung condition in the United States- approximately 26 million children and adults suffer from it. With so many people having this condition, there are bound to be rumors and myths that come with it. Today, we will fact-check some of these myths to create more safety and awareness for those with asthma.

Myth: Children can outgrow asthma.1

Truth: Asthma can go into periods of remission or may be so well controlled that symptoms are not experienced for long periods. Once you have asthma, you’ll always have asthma.

Myth: Asthma is difficult to control. 3

Truth: It can be well-controlled with the right treatment options available to you.

Myth: You can stop medication during the seasons that you don’t have any exposure to your asthma triggers.1

Truth: It’s important for you to continue your asthma action plan and take your medication to keep control of your asthma. Your doctor may tell you to reduce your medication if it is well under control, however, it is very dangerous to stop without supervision.

Myth: Pregnant women with asthma should not take the flu shot.1

Truth: Pregnant women should get the flu shot when it’s available. Getting the vaccine is protecting them, and via the placenta, giving the baby some flu immunity, too.

Myth: Asthma medication is dangerous and can be addicting.4

Truth: No asthma medication used in the U.S. is habit-forming or addicting. Although some medications are inhaled corticosteroids, these are not related to the steroids used for muscle growth (for athletes).

Myth: Asthma can’t be fatal.5

Truth: It is rare, but fatalities can happen. The rate of death due to asthma has been decreasing since 2001

Myth: My child has asthma and shouldn’t be allowed to play outside or play any sports.7

Truth: All kids need to exercise and be healthy. As long as a child with controlled asthma takes their medication before they play outside or join a sport, they should be able to keep up. If the child has uncontrolled asthma, they may develop symptoms as they play.

Myth: Asthma symptoms are the same for everyone.2

Truth: Asthma affects each person differently. One person might show several symptoms and others may just cough.

Myth: Asthma is all in your mind.2

Truth: Asthma is hard to predict but can be very serious. There can be underlying inflammation in the airways in people with asthma. Asthma doesn’t just go away when symptoms are gone.

Myth: Asthma medication becomes less effective over time.6

Truth: If you have an asthma attack, it may not be that your medication has stopped working- it may just be the air quality or you are being exposed to a new environmental trigger. Although if it is noticeable that you’re having a difficult time controlling your asthma, contact your doctor and find ways to better manage or change your medication.

If you have any questions about how to maintain your asthma, please give us a call and schedule an appointment with one of our board-certified providers to help you find the best ways to help. 210-616-0882.